Magne B6: magnesium + B6 dosing and safety essentials

Theme

Magnesium + vitamin B6 medicinal product · clinical use guardrails

Magne B6: correcting magnesium deficiency safely in adults and children 6+

Source
Source: Листок-вкладыш для пациента: «Магне В6®, 48 мг+5 мг, таблетки, покрытые оболочкой» (магний + пиридоксин), файл Approved-PIL-L-26.12.2023. Trial/study name not present.

For suspected or confirmed magnesium deficiency, dosing is age- and weight-based; renal function, levodopa, sugar content, pregnancy/lactation status and adverse effects materially change the risk–benefit assessment.

Magne-B6
Product Coated tablet; magnesium lactate dihydrate + pyridoxine hydrochloride.
Population Adults; children over 6 years and weighing more than 20 kg.
Duration Use during deficiency correction; stop once blood magnesium normalizes.
Comparator No trial comparator: label-based dosing and safety guidance.
Hero fact per coated tablet
48 mg elemental magnesium per tablet
5 mg pyridoxine vitamin B6 per tablet
115.6 mg sucrose per tablet — relevant in diabetes or sugar intolerance

What it is for

Magne B6 is used to replenish magnesium deficiency. Symptoms compatible with deficiency may include neuromuscular, sleep, gastrointestinal or cardiovascular complaints; persistent or severe symptoms warrant medical evaluation.

Irritability
Mild sleep problems
Fatigue
Muscle pain or spasms
Tingling
GI spasms
Palpitations

High-risk exclusions

Renal contraindication

CrCl <30 ml/min: severe renal failure; do not use.

Age restriction

<6 yrs contraindicated in children under 6 years.

Drug interaction

Levodopa do not take together with Magne B6.

Pediatric threshold

6+ yrs & >20 kg minimum label population for pediatric tablet dosing.

How to take it: split daily dose with meals

Population Tablets/day Elemental Mg/day Vitamin B6/day Administration
Adults 6–8 288–384 mg 30–40 mg Divide into 2–3 doses, taken with meals.
Children >6 years and >20 kg 4–6 192–288 mg 20–30 mg Divide into 2–3 doses, taken with meals.

Daily magnesium and vitamin B6 totals are derived from the per-tablet content: 48 mg elemental magnesium + 5 mg pyridoxine vitamin B6.

Key finding 1 · recommended dose

6–8 tabs per day in adults; children over 6 years and >20 kg take 4–6 tablets/day. Divide into 2–3 doses with meals.

Key finding 2 · do not use

CrCl <30 ml/min contraindicated in severe renal failure; also contraindicated in children under 6 years and with levodopa.

Key finding 3 · formulation detail

115.6 mg sucrose per coated tablet; clinically relevant for diabetes counselling and rare sugar-intolerance syndromes.

Who should avoid or use caution

Do not use Severe renal impairment, defined as creatinine clearance below 30 ml/min; children under 6 years; concomitant levodopa.
Renal caution Moderate kidney impairment increases magnesium accumulation risk; consult a doctor before use.
Pregnancy / lactation Pregnancy: use only if necessary and on a doctor’s recommendation; if use is necessary during breastfeeding, stopping breastfeeding is recommended.
Diabetes / sugar intolerance Each tablet contains 115.6 mg sucrose; assess total daily sucrose exposure and rare hereditary sugar intolerance.
Interacting medicines Do not take with oral tetracyclines, phosphate-containing products, calcium salts, iron ions or quinolones because this may reduce effect.
Treatment endpoint Stop supplementation once blood magnesium normalizes; reassess if symptoms persist despite appropriate use.

Safety essentials

Adverse reactions Possible gastrointestinal symptoms such as diarrhea or abdominal pain; skin reactions or allergy can occur.
Overdose risk Risk is highest with impaired renal function; hypermagnesemia may cause nausea, hypotension, CNS depression, respiratory depression or cardiac effects.
Storage Keep out of reach of children; store at a temperature not above 25°C; do not use after the expiry date.

Numbers to know

48 mg elemental magnesium per tablet
5 mg pyridoxine vitamin B6 per tablet
2–3 doses split across meals each day
<30 ml/min creatinine clearance threshold for severe renal failure contraindication
115.6 mg sucrose per coated tablet
6+ & >20 kg minimum pediatric age and weight for tablet dosing
Use Magne B6 only for suspected or confirmed magnesium deficiency and follow age-based dosing; consult a doctor before use if pregnant, breastfeeding, diabetic, taking interacting medicines, or having kidney problems — and stop treatment once blood magnesium normalizes.

Before use, read the patient information leaflet. If adverse effects occur, symptoms worsen, or deficiency symptoms persist, seek medical advice. This infographic supports clinical communication and does not replace local prescribing information.

AbbreviationsQuick
Abbreviations: Mg²⁺ — магний; ПВХ — поливинилхлорид.
Bibliography1
  1. Листок-вкладыш – информация для пациента. Магне В6®, 48 мг+5 мг, таблетки, покрытые оболочкой; действующее вещество: магний + пиридоксин. Держатель регистрационного удостоверения: Opella Healthcare Commercial Ltd. Approved PIL-L, 26.12.2023.
✔Числа сверены с источником · Numbers verified against source
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